Publications 2016
miR-125b controls monocyte adaptation to inflammation through mitochondrial metabolism and dynamics.
Duroux-Richard I, Roubert C, Ammari M, Présumey J, Grün JR, Häupl T, Grützkau A, Lecellier CH, Boitez V, Codogno P, Escoubet J, Pers YM, Jorgensen C, Apparailly F.
Blood. 2016 Oct 4. pii: blood-2016-02-697003
Utility of a Mouse Model of Osteoarthritis to Demonstrate Cartilage Protection by IFNγ-Primed Equine Mesenchymal Stem Cells.
Maumus M, Roussignol G, Toupet K, Penarier G, Bentz I, Teixeira S, Oustric D, Jung M, Lepage O, Steinberg R, Jorgensen C, Noel D.
Front Immunol. 2016 Sep 27;7:392
Mastitis associated with Sjögren's syndrome: a series of nine cases.
Goulabchand R, Hafidi A, Millet I, Morel J, Lukas C, Humbert S, Rivière S, Gény C, Jorgensen C, Le Quellec A, Perrochia H, Guilpain P.
Immunol Res. 2016 Aug 25.
Perspectives of ofatumumab as CD20 targeted therapy in rheumatoid arthritis and other autoimmune diseases.
Pers YM, Jorgensen C.
Immunotherapy. 2016 Sep;8(9):1091-6. doi: 10.2217/imt-2016-0003.
Remission-induction therapies for early rheumatoid arthritis: evidence to date and clinical implications.
Espinoza F, Fabre S, Pers YM.
Ther Adv Musculoskelet Dis. 2016 Aug;8(4):107-18
Non-TNF-Targeted Biologic vs a Second Anti-TNF Drug to Treat Rheumatoid Arthritis in Patients With Insufficient Response to a First Anti-TNF Drug: A Randomized Clinical Trial.
Gottenberg JE, Brocq O, Perdriger A, Lassoued S, Berthelot JM, Wendling D, Euller-Ziegler L, Soubrier M, Richez C, Fautrel B, Constantin AL, Mariette X, Morel J, Gilson M, Cormier G, Salmon JH, Rist S, Lioté F, Marotte H, Bonnet C, Marcelli C, Sellam J, Meyer O, Solau-Gervais E, Guis S, Ziza JM, Zarnitsky C, Chary-Valckenaere I, Vittecoq O, Saraux A, Pers YM, Gayraud M, Bolla G, Claudepierre P, Ardizzone M, Dernis E, Breban MA, Fain O, Balblanc JC, Aberkane O, Vazel M, Back C, Candon S, Chatenoud L, Perrodeau E, Sibilia J, Ravaud P.
JAMA. 2016 Sep 20;316(11):1172-1180. doi: 10.1001/jama.2016.13512.
Essential Competencies in Prescribing: A First European Cross-Sectional Study Among 895 Final-Year Medical Students.
Brinkman DJ, Tichelaar J, Schutte T, Benemei S, Böttiger Y, Chamontin B, Christiaens T, Likic R, Mačiulaitis R, Marandi T, Monteiro EC, Papaioannidou P, Pers YM, Pontes C, Raskovic A, Regenthal R, Sanz EJ, Tamba BI, Wilson K, de Vries TP, Richir MC, van Agtmael MA; Working Group Research on CPT Education of the European Association for Clinical Pharmacology and Therapeutics (EACPT).
Clin Pharmacol Ther. 2016 Sep 20. doi: 10.1002/cpt.521.
Tocilizumab and mesenteric arterial thrombosis: drug-drug interaction with anticoagulants metabolized by CYP 450 and/or by P-glycoprotein.
Clarivet B, Robin P, Pers YM, Ferreira R, Lebrun J, Jorgensen C, Hillaire-Buys D, Brés V, Faillie JL.
Eur J Clin Pharmacol. 2016 Nov;72(11):1413-1414
Deregulation and therapeutic potential of microRNAs in arthritic diseases.
Vicente R, Noël D, Pers YM, Apparailly F, Jorgensen C.
Nat Rev Rheumatol. 2016 Aug;12(8):496. doi: 10.1038/nrrheum.2016.119
Association of TRAF1-C5 with risk of uveitis in juvenile idiopathic arthritis.
Pers YM, Le Blay P, Ludwig C, Rittore C, Tejedor G, Foliwe R, Rodiere M, Jorgensen C, Touitou I.
Joint Bone Spine. 2016 Jun 28
Interferon α kinoid induces neutralizing anti-interferon α antibodies that decrease the expression of interferon-induced and B cell activation associated transcripts: analysis of extended follow-up data from the interferon α kinoid phase I/II study.
Ducreux J, Houssiau FA, Vandepapelière P, Jorgensen C, Lazaro E, Spertini F, Colaone F, Roucairol C, Laborie M, Croughs T, Grouard-Vogel G, Lauwerys BR.
Rheumatology (Oxford). 2016 Oct;55(10):1901-5
Effects of alcohol withdrawal on monocyte subset defects in chronic alcohol users.
Donnadieu-Rigole H, Mura T, Portales P, Duroux-Richard I, Bouthier M, Eliaou JF, Perney P, Apparailly F.
J Leukoc Biol. 2016 Jun 2.
Comparison between Stromal Vascular Fraction and Adipose Mesenchymal Stem Cells in Remodeling Hypertrophic Scars.
Domergue S, Bony C, Maumus M, Toupet K, Frouin E, Rigau V, Vozenin MC, Magalon G, Jorgensen C, Noël D.
PLoS One. 2016 May 26;11(5):e0156161. doi: 10.1371/journal.pone.0156161
Adipose Mesenchymal Stromal Cell-Based Therapy for Severe Osteoarthritis of the Knee: A Phase I Dose-Escalation Trial.
Pers YM, Rackwitz L, Ferreira R, Pullig O, Delfour C, Barry F, Sensebe L, Casteilla L, Fleury S, Bourin P, Noël D, Canovas F, Cyteval C, Lisignoli G, Schrauth J, Haddad D, Domergue S, Noeth U, Jorgensen C; ADIPOA Consortium.
Stem Cells Transl Med. 2016 May 23. pii: sctm.2015-0245
Mesenchymal stem cell transplantation in systemic sclerosis: Reply to the comment from P Cipriani et al.
Tj Maria A, Jorgensen C, Le Quellec A, Noël D, Guilpain P.
Arthritis Rheumatol. 2016 May 23. doi: 10.1002/art.39756
Adipose-Derived Mesenchymal Stem Cells in Autoimmune Disorders: State of the Art and Perspectives for Systemic Sclerosis.
Maria AT, Maumus M, Le Quellec A, Jorgensen C, Noël D, Guilpain P.
Clin Rev Allergy Immunol. 2016 May 20.
Adipose derived stem cells for regenerative therapy in osteoarticular diseases.
Pers YM, Jorgensen C.
Horm Mol Biol Clin Investig. 2016 Apr 19. pii: /j/hmbci.ahead-of-print/hmbci-2016-0010/hmbci-2016-0010.xml. doi: 10.1515/hmbci-2016-0010
Human adipose mesenchymal stem cells as potent anti-fibrosis therapy for systemic sclerosis.
Maria AT, Toupet K, Maumus M, Fonteneau G, Le Quellec A, Jorgensen C, Guilpain P, Noël D.
J Autoimmun. 2016 Jun;70:31-9. doi: 10.1016/j.jaut.2016.03.013
PLGA-based microcarriers induce mesenchymal stem cell chondrogenesis and stimulate cartilage repair in osteoarthritis.
Morille M, Toupet K, Montero-Menei CN, Jorgensen C, Noël D.
Biomaterials. 2016 May;88:60-9. doi: 10.1016/j.biomaterials.2016.02.022
Cellular senescence impact on immune cell fate and function.
Vicente R, Mausset-Bonnefont AL, Jorgensen C, Louis-Plence P, Brondello JM.
Aging Cell. 2016 Jun;15(3):400-6. doi: 10.1111/acel.12455.
Handgrip strength measured by a dynamometer connected to a smartphone: a new applied health technology solution for the self-assessment of rheumatoid arthritis disease activity.
Espinoza F, Le Blay P, Coulon D, Lieu S, Munro J, Jorgensen C, Pers YM.
Rheumatology (Oxford). 2016 May;55(5):897-901. doi: 10.1093/rheumatology/kew006
Adipose Mesenchymal Stem Cells Isolated after Manual or Water-jet-Assisted Liposuction Display Similar Properties.
Bony C, Cren M, Domergue S, Toupet K, Jorgensen C, Noël D.
Front Immunol. 2016 Jan 18;6:655. doi: 10.3389/fimmu.2015.00655
Deregulation and therapeutic potential of microRNAs in arthritic diseases.
Vicente R, Noël D, Pers YM, Apparailly F, Jorgensen C.
Nat Rev Rheumatol. 2016 Apr;12(4):211-20. doi: 10.1038/nrrheum.2015.162.
Mesenchymal Stem Cell-Derived Interleukin 1 Receptor Antagonist Promotes Macrophage Polarization and Inhibits B Cell Differentiation.
Luz-Crawford P, Djouad F, Toupet K, Bony C, Franquesa M, Hoogduijn MJ, Jorgensen C, Noël D.
Stem Cells. 2016 Feb;34(2):483-92. doi: 10.1002/stem.2254
The immunosuppressive signature of menstrual blood mesenchymal stem cells entails opposite effects on experimental arthritis and graft versus host diseases.
Luz-Crawford P, Torres MJ, Noël D, Fernandez A, Toupet K, Alcayaga-Miranda F, Tejedor G, Jorgensen C, Illanes SE, Figueroa FE, Djouad F, Khoury M.
Stem Cells. 2016 Feb;34(2):456-69. doi: 10.1002/stem.2244
Antifibrotic, Antioxidant, and Immunomodulatory Effects of Mesenchymal Stem Cells in HOCl-Induced Systemic Sclerosis.
Maria AT, Toupet K, Bony C, Pirot N, Vozenin MC, Petit B, Roger P, Batteux F, Le Quellec A, Jorgensen C, Noël D, Guilpain P.
Arthritis Rheumatol. 2016 Apr;68(4):1013-25. doi: 10.1002/art.39477.
Nonclassical CD4+CD49b+ Regulatory T Cells as a Better Alternative to Conventional CD4+CD25+ T Cells To Dampen Arthritis Severity.
Vicente R, Quentin J, Mausset-Bonnefont AL, Chuchana P, Martire D, Cren M, Jorgensen C, Louis-Plence P.
J Immunol. 2016 Jan 1;196(1):298-309. doi: 10.4049/jimmunol.1501069
Therapeutic application of mesenchymal stem cells in osteoarthritis.
Ruiz M, Cosenza S, Maumus M, Jorgensen C, Noël D.
Expert Opin Biol Ther. 2016 Jan;16(1):33-42. doi: 10.1517/14712598.2016.1093108. Epub 2015 Sep 28
Inhibition of Osteoarthritis by Adipose-Derived Stromal Cells Overexpressing Fra-1 in Mice.
Schwabe K, Garcia M, Ubieta K, Hannemann N, Herbort B, Luther J, Noël D, Jorgensen C, Casteilla L, David JP, Stock M, Herrmann M, Schett G, Bozec A.
Arthritis Rheumatol. 2016 Jan;68(1):138-51. doi: 10.1002/art.39425.
Duroux-Richard I, Roubert C, Ammari M, Présumey J, Grün JR, Häupl T, Grützkau A, Lecellier CH, Boitez V, Codogno P, Escoubet J, Pers YM, Jorgensen C, Apparailly F.
Blood. 2016 Oct 4. pii: blood-2016-02-697003
Utility of a Mouse Model of Osteoarthritis to Demonstrate Cartilage Protection by IFNγ-Primed Equine Mesenchymal Stem Cells.
Maumus M, Roussignol G, Toupet K, Penarier G, Bentz I, Teixeira S, Oustric D, Jung M, Lepage O, Steinberg R, Jorgensen C, Noel D.
Front Immunol. 2016 Sep 27;7:392
Mastitis associated with Sjögren's syndrome: a series of nine cases.
Goulabchand R, Hafidi A, Millet I, Morel J, Lukas C, Humbert S, Rivière S, Gény C, Jorgensen C, Le Quellec A, Perrochia H, Guilpain P.
Immunol Res. 2016 Aug 25.
Perspectives of ofatumumab as CD20 targeted therapy in rheumatoid arthritis and other autoimmune diseases.
Pers YM, Jorgensen C.
Immunotherapy. 2016 Sep;8(9):1091-6. doi: 10.2217/imt-2016-0003.
Remission-induction therapies for early rheumatoid arthritis: evidence to date and clinical implications.
Espinoza F, Fabre S, Pers YM.
Ther Adv Musculoskelet Dis. 2016 Aug;8(4):107-18
Non-TNF-Targeted Biologic vs a Second Anti-TNF Drug to Treat Rheumatoid Arthritis in Patients With Insufficient Response to a First Anti-TNF Drug: A Randomized Clinical Trial.
Gottenberg JE, Brocq O, Perdriger A, Lassoued S, Berthelot JM, Wendling D, Euller-Ziegler L, Soubrier M, Richez C, Fautrel B, Constantin AL, Mariette X, Morel J, Gilson M, Cormier G, Salmon JH, Rist S, Lioté F, Marotte H, Bonnet C, Marcelli C, Sellam J, Meyer O, Solau-Gervais E, Guis S, Ziza JM, Zarnitsky C, Chary-Valckenaere I, Vittecoq O, Saraux A, Pers YM, Gayraud M, Bolla G, Claudepierre P, Ardizzone M, Dernis E, Breban MA, Fain O, Balblanc JC, Aberkane O, Vazel M, Back C, Candon S, Chatenoud L, Perrodeau E, Sibilia J, Ravaud P.
JAMA. 2016 Sep 20;316(11):1172-1180. doi: 10.1001/jama.2016.13512.
Essential Competencies in Prescribing: A First European Cross-Sectional Study Among 895 Final-Year Medical Students.
Brinkman DJ, Tichelaar J, Schutte T, Benemei S, Böttiger Y, Chamontin B, Christiaens T, Likic R, Mačiulaitis R, Marandi T, Monteiro EC, Papaioannidou P, Pers YM, Pontes C, Raskovic A, Regenthal R, Sanz EJ, Tamba BI, Wilson K, de Vries TP, Richir MC, van Agtmael MA; Working Group Research on CPT Education of the European Association for Clinical Pharmacology and Therapeutics (EACPT).
Clin Pharmacol Ther. 2016 Sep 20. doi: 10.1002/cpt.521.
Tocilizumab and mesenteric arterial thrombosis: drug-drug interaction with anticoagulants metabolized by CYP 450 and/or by P-glycoprotein.
Clarivet B, Robin P, Pers YM, Ferreira R, Lebrun J, Jorgensen C, Hillaire-Buys D, Brés V, Faillie JL.
Eur J Clin Pharmacol. 2016 Nov;72(11):1413-1414
Deregulation and therapeutic potential of microRNAs in arthritic diseases.
Vicente R, Noël D, Pers YM, Apparailly F, Jorgensen C.
Nat Rev Rheumatol. 2016 Aug;12(8):496. doi: 10.1038/nrrheum.2016.119
Association of TRAF1-C5 with risk of uveitis in juvenile idiopathic arthritis.
Pers YM, Le Blay P, Ludwig C, Rittore C, Tejedor G, Foliwe R, Rodiere M, Jorgensen C, Touitou I.
Joint Bone Spine. 2016 Jun 28
Interferon α kinoid induces neutralizing anti-interferon α antibodies that decrease the expression of interferon-induced and B cell activation associated transcripts: analysis of extended follow-up data from the interferon α kinoid phase I/II study.
Ducreux J, Houssiau FA, Vandepapelière P, Jorgensen C, Lazaro E, Spertini F, Colaone F, Roucairol C, Laborie M, Croughs T, Grouard-Vogel G, Lauwerys BR.
Rheumatology (Oxford). 2016 Oct;55(10):1901-5
Effects of alcohol withdrawal on monocyte subset defects in chronic alcohol users.
Donnadieu-Rigole H, Mura T, Portales P, Duroux-Richard I, Bouthier M, Eliaou JF, Perney P, Apparailly F.
J Leukoc Biol. 2016 Jun 2.
Comparison between Stromal Vascular Fraction and Adipose Mesenchymal Stem Cells in Remodeling Hypertrophic Scars.
Domergue S, Bony C, Maumus M, Toupet K, Frouin E, Rigau V, Vozenin MC, Magalon G, Jorgensen C, Noël D.
PLoS One. 2016 May 26;11(5):e0156161. doi: 10.1371/journal.pone.0156161
Adipose Mesenchymal Stromal Cell-Based Therapy for Severe Osteoarthritis of the Knee: A Phase I Dose-Escalation Trial.
Pers YM, Rackwitz L, Ferreira R, Pullig O, Delfour C, Barry F, Sensebe L, Casteilla L, Fleury S, Bourin P, Noël D, Canovas F, Cyteval C, Lisignoli G, Schrauth J, Haddad D, Domergue S, Noeth U, Jorgensen C; ADIPOA Consortium.
Stem Cells Transl Med. 2016 May 23. pii: sctm.2015-0245
Mesenchymal stem cell transplantation in systemic sclerosis: Reply to the comment from P Cipriani et al.
Tj Maria A, Jorgensen C, Le Quellec A, Noël D, Guilpain P.
Arthritis Rheumatol. 2016 May 23. doi: 10.1002/art.39756
Adipose-Derived Mesenchymal Stem Cells in Autoimmune Disorders: State of the Art and Perspectives for Systemic Sclerosis.
Maria AT, Maumus M, Le Quellec A, Jorgensen C, Noël D, Guilpain P.
Clin Rev Allergy Immunol. 2016 May 20.
Adipose derived stem cells for regenerative therapy in osteoarticular diseases.
Pers YM, Jorgensen C.
Horm Mol Biol Clin Investig. 2016 Apr 19. pii: /j/hmbci.ahead-of-print/hmbci-2016-0010/hmbci-2016-0010.xml. doi: 10.1515/hmbci-2016-0010
Human adipose mesenchymal stem cells as potent anti-fibrosis therapy for systemic sclerosis.
Maria AT, Toupet K, Maumus M, Fonteneau G, Le Quellec A, Jorgensen C, Guilpain P, Noël D.
J Autoimmun. 2016 Jun;70:31-9. doi: 10.1016/j.jaut.2016.03.013
PLGA-based microcarriers induce mesenchymal stem cell chondrogenesis and stimulate cartilage repair in osteoarthritis.
Morille M, Toupet K, Montero-Menei CN, Jorgensen C, Noël D.
Biomaterials. 2016 May;88:60-9. doi: 10.1016/j.biomaterials.2016.02.022
Cellular senescence impact on immune cell fate and function.
Vicente R, Mausset-Bonnefont AL, Jorgensen C, Louis-Plence P, Brondello JM.
Aging Cell. 2016 Jun;15(3):400-6. doi: 10.1111/acel.12455.
Handgrip strength measured by a dynamometer connected to a smartphone: a new applied health technology solution for the self-assessment of rheumatoid arthritis disease activity.
Espinoza F, Le Blay P, Coulon D, Lieu S, Munro J, Jorgensen C, Pers YM.
Rheumatology (Oxford). 2016 May;55(5):897-901. doi: 10.1093/rheumatology/kew006
Adipose Mesenchymal Stem Cells Isolated after Manual or Water-jet-Assisted Liposuction Display Similar Properties.
Bony C, Cren M, Domergue S, Toupet K, Jorgensen C, Noël D.
Front Immunol. 2016 Jan 18;6:655. doi: 10.3389/fimmu.2015.00655
Deregulation and therapeutic potential of microRNAs in arthritic diseases.
Vicente R, Noël D, Pers YM, Apparailly F, Jorgensen C.
Nat Rev Rheumatol. 2016 Apr;12(4):211-20. doi: 10.1038/nrrheum.2015.162.
Mesenchymal Stem Cell-Derived Interleukin 1 Receptor Antagonist Promotes Macrophage Polarization and Inhibits B Cell Differentiation.
Luz-Crawford P, Djouad F, Toupet K, Bony C, Franquesa M, Hoogduijn MJ, Jorgensen C, Noël D.
Stem Cells. 2016 Feb;34(2):483-92. doi: 10.1002/stem.2254
The immunosuppressive signature of menstrual blood mesenchymal stem cells entails opposite effects on experimental arthritis and graft versus host diseases.
Luz-Crawford P, Torres MJ, Noël D, Fernandez A, Toupet K, Alcayaga-Miranda F, Tejedor G, Jorgensen C, Illanes SE, Figueroa FE, Djouad F, Khoury M.
Stem Cells. 2016 Feb;34(2):456-69. doi: 10.1002/stem.2244
Antifibrotic, Antioxidant, and Immunomodulatory Effects of Mesenchymal Stem Cells in HOCl-Induced Systemic Sclerosis.
Maria AT, Toupet K, Bony C, Pirot N, Vozenin MC, Petit B, Roger P, Batteux F, Le Quellec A, Jorgensen C, Noël D, Guilpain P.
Arthritis Rheumatol. 2016 Apr;68(4):1013-25. doi: 10.1002/art.39477.
Nonclassical CD4+CD49b+ Regulatory T Cells as a Better Alternative to Conventional CD4+CD25+ T Cells To Dampen Arthritis Severity.
Vicente R, Quentin J, Mausset-Bonnefont AL, Chuchana P, Martire D, Cren M, Jorgensen C, Louis-Plence P.
J Immunol. 2016 Jan 1;196(1):298-309. doi: 10.4049/jimmunol.1501069
Therapeutic application of mesenchymal stem cells in osteoarthritis.
Ruiz M, Cosenza S, Maumus M, Jorgensen C, Noël D.
Expert Opin Biol Ther. 2016 Jan;16(1):33-42. doi: 10.1517/14712598.2016.1093108. Epub 2015 Sep 28
Inhibition of Osteoarthritis by Adipose-Derived Stromal Cells Overexpressing Fra-1 in Mice.
Schwabe K, Garcia M, Ubieta K, Hannemann N, Herbort B, Luther J, Noël D, Jorgensen C, Casteilla L, David JP, Stock M, Herrmann M, Schett G, Bozec A.
Arthritis Rheumatol. 2016 Jan;68(1):138-51. doi: 10.1002/art.39425.
